ACTIVE is located within the Moorfields Biomedical Research Centre, a world-class Centre of excellence for ophthalmic research, pioneering world leading gene & stem cell therapies, new drug treatments and novel diagnostic devices for management of visual impairment.
The remit of ACTIVE is to increase clinical trial activity in ophthalmology and develop a methodological hub for all aspects of the design, conduct and reporting of trials. Specific activities focus on research into cost-efficiencies in trial conduct, strategies for improving recruitment and the development of core and patient orientated outcome sets for eye and vision trials.
ACTIVE Hub & Spoke Model
The Centre links with the Ophthalmic Statistics Group which has an aim to ‘raise the standards of statistics in ophthalmic research’; and is formally linked with the Cochrane Eyes and Vision Group and the newly established UCL Clinical Trials Unit (UCL- CTU).
ACTIVE is led jointly by Mr Richard Wormald (Consultant Ophthalmologist - Moorfields Eye Hospital and Coordinating Editor - Cochrane Eyes and Vision Group) and Dr Catey Bunce (Principal Statistician - Moorfields Eye Hospital and Statistical Editor - Cochrane Eyes and Vision Group).
ACTIVE also includes Dr Mays Jaward (Research Portfolio Manager - Moorfields Eye Hospital), Ms Ana Quartilho (Senior Medical Statistician - Moorfields Eye Hospital), Professor Gary Rubin (Head of Visual Neuroscience - UCL Institute of Ophthalmology) and Dr Andi Skilton (PPI/E Senior Research Associate Lead - NIHR Moorfields Biomedical Research Centre).
ACTIVE helps research teams throughout the country design clinical trials safely and to a high scientific standard, offering a range of services to help ensure the results are accurate and credible. The Centre’s services are available to researchers, throughout Moorfields, UCLPartners and other academic and industrial partners.
ACTIVE offers comprehensive support to trials across all ophthalmic disease areas in MEH/UCL that are funded by NIHR HTA, NIHR EME, NIHR SDO, NIHR PHR, NIHR HSR and NIHR RfPB. Other trials may be accepted onto the portfolio for support on a case by case basis.
*ACTIVE is currently at capacity (as of Monday 25 April 2016) and is unable to accept new applications for the time being. Please check back here over the coming weeks for an update on our status*
In the meantime, if you are seeking advice regarding a research funding application please consider contacting your local NIHR Research Design Service.
To find out more about ACTIVE services please use our contact us page or download our Trial Proposal Form to provide details of your enquiry. Our criteria for adoption of studies can be downloaded here.